PEP after Non-Occupational and Occupational Exposure to HIV: Australian Guidelines revised

Our apologies to those who tried to access SASHA while it was down. The technical difficulties have now been resolved.

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Australasian Society for HIV, Viral Hepatitis and Sexual Health Medicine, August 2016

The Second edition of the Post-Exposure Prophylaxis after Non-Occupational and Occupational Exposure to HIV: Australian National Guidelines is now available.

These guidelines outline the management of individuals who have been exposed (or suspect they have been exposed) to HIV in non-occupational and occupational settings.

There are currently no data from randomised controlled trials of the use of post-exposure prophylaxis (PEP) and evidence for use has been extrapolated from animal data, mother to child transmission, occupational exposure and small prospective studies of PEP regimens in HIV-negative men. Accordingly, assumptions are made about the direction of management.

Every presentation for PEP should be assessed on a case-by-case basis, balancing the potential harms and benefits of treatment.

Recommendations following non-occupational exposure have been updated, and information about PEP in the context of pre-exposure prophylaxis (PrEP), PEP and children, renal disease, and gender identity and history has been added.

  • Download the revised guidelines (PDF) here
  • Updates to the supplementary documents, as well as a navigable website for the guidelines, will soon be available. At present, the 2013 literature review and checklist are still available, linked below:

    PEP Checklist (2013)

    Literature Review (2013)

 

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