Taglatent HIV reservoirs

HIV reservoirs are established earlier than expected

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The European AIDS Treatment Group (EATG), February 2023 For the first time in humans, a research team has shown that, as early as the first days of infection, HIV is able to create reservoirs where it will hide and persist during antiretroviral therapy. Until now, the scientific community did not know exactly when or how these viral reservoirs—the existence of which is a major obstacle to curing...

Child Living with HIV Maintains Remission Without Drugs Since 2008

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National Institute of Allergy and Infectious Diseases (NIAID), July 24, 2017 A nine-year-old South African child who was diagnosed with HIV infection at one month of age and received anti-HIV treatment during infancy has suppressed the virus without anti-HIV drugs for eight and a half years, scientists reported today at the 9th IAS Conference on HIV Science in Paris. This case appears to be the...

‘Shock and kill’ therapy offers fresh hope for HIV cure, researchers say

PBS Newshour, December 15, 2016 at 11:00 AM EST A new small-scale human trial of the promising “shock and kill” treatment is starting this week in New York and two sister sites, in Germany and Denmark.  Another small human study will start in January, followed by a larger human shock and kill trial in June. The HIV research community is increasingly optimistic about this approach to eradicating...

Even in undetectable patients, HIV is still replicating in the lymphoid tissues

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Slate, January 27 2016 While progress toward a vaccine and even a functional cure for HIV has accelerated in recent years, a major obstacle has been the “viral reservoir”—locations and cell types in a body where the virus can persist at very low levels even when treatment has succeeded at making it undetectable in the blood by standard testing. Published in the Jan. 27 issue of Nature, a new...

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