U.S. FDA Approves Evofem Biosciences’ Phexxi™, the First Non-Hormonal Prescription Gel for the Prevention of Pregnancy

Evofem Biosciences via PRNewswire, May 22nd 2020 

Evofem Biosciences, Inc. today announced that the U.S. Food and Drug Administration (FDA) has approved Phexxi™ (lactic acid, citric acid and potassium bitartrate) vaginal gel for the prevention of pregnancy in females of reproductive potential for use as an on-demand method of contraception.

Phexxi is the first non-hormonal, on-demand, vaginal pH regulator contraceptive designed to maintain vaginal pH within the normal range of 3.5 to 4.5 – an acidic environment that is inhospitable to sperm.

COVID-19: pregnancy, childbirth and breastfeeding – statements & guidance

Various sources, March 2020

Psychosocial mediators of perceived stigma and suicidal ideation among transgender women

Kota, K.K., Salazar, L.F., Culbreth, R.E. et al. Psychosocial mediators of perceived stigma and suicidal ideation among transgender women. BMC Public Health 20125 (2020). https://doi.org/10.1186/s12889-020-8177-z

Abstract

Background

Transgender women (TGW) in the U.S. experience high rates of stigma, depression, and elevated rates of suicide. This study examined correlates of suicidal ideation and estimated the conditional indirect effects of perceived stigma and psychosocial mediators on suicidal ideation.

Methods

Using a cross-sectional study design, TGW (N = 92) were recruited through snowball sampling in Atlanta, Georgia. Structured interviews were conducted. Suicidal ideation was assessed by combining two variables that measured suicidal thoughts. Logistic regression models were performed to identify the potential risk and protective factors for suicidal ideation. We examined hypothesized psychosocial factors, including anxiety, depression, psychosocial impact of gender minority status, and substance use behaviors as potential mediators for the relationship between perceived stigma and suicidal ideation. All models were controlled for age, race, education, and homelessness.

Results

Suicidal ideation was reported by 33% (N = 30) of the study participants. In multivariable analysis, suicidal ideation was associated with sexual abuse (AOR = 3.17, 95% CI = 1.10–9.30), anxiety (AOR = 1.74, 95% CI = 1.10–2.73), family verbal abuse (AOR = 2.99, 95% CI = 1.10–8.40), stranger verbal abuse (AOR = 3.21, 95% CI = 1.02–10.08), and psychosocial impact of gender minority status (AOR = 3.42, 95% CI = 1.81–6.46). Partner support was found to be the protective factor for suicidal ideation (AOR = 0.34, 95% CI = 0.13–0.90). In the mediation analysis, the psychosocial impact of gender minority status mediated the relationship between perceived stigma and suicidal ideation. The estimated conditional indirect effect was 0.46, (95% CI = 0.12–1.11).

Conclusion

Interventions that aim to reduce suicidal behaviors among TGW should address stigma, psychosocial imfamilpact of gender minority status, and different forms of violence and abuse.

Among transgender children, gender identity as strong as in cisgender children, study shows

University of Washington, November 18, 2019

Children who identify as the gender matching their sex at birth tend to gravitate toward the toys, clothing and friendships stereotypically associated with that gender.

Transgender children do the same with the gender they identify as, regardless of how long they have actually lived as a member of that gender. New findings from the largest study of socially-transitioned transgender children in the world, conducted by researchers at the University of Washington, show that gender identity and gender-typed preferences manifest similarly in both cis- and transgender children, even those who recently transitioned.

The study, published Nov. 18 in the Proceedings of the National Academy of Sciences, followed more than 300 transgender children from across the United States, as well as nearly 200 of their cisgender siblings and about 300 unrelated cisgender children as a control group.

SHINE SA and FPAA condemn Alabama law to ban abortions (media release)

On 17 May 2019, Family Planning Alliance Australia (FPAA) released a statement condemning a new law in Alabama which makes abortion a crime in almost all cases. This is the most restrictive abortion law in the United States and follows a wave of anti-abortion laws in 2019¹.

FPAA state:

“The restrictive and extreme abortion ban violates women’s reproductive rights and penalises health care practitioners for providing basic health care. As an organisation committed to empowering reproductive choice and improving access to health care, we find this law disturbing and unjust.”

Natasha Miliotis, SHINE SA’s Chief Executive Officer said that:

“SHINE SA supports the FPAA statement and recognises that access to safe abortion services reduces the mortality and morbidity that occurs as a result of dangerous and illegal abortion. This is evidenced by a higher frequency of abortion-related deaths in countries with restrictive abortion laws than in countries with less restrictive laws².

SHINE SA, a member of FPAA, advocates for reproductive freedom and for provision of legal, safe, affordable and accessible abortion in Australia and worldwide. We recognise that trans, gender diverse and intersex people may also need access to abortion, but also that measures such as this disproportionately affect women.

SHINE SA believes that both medical and surgical abortion are safe and effective health interventions and that abortion is a private medical decision that should not be politicised.”

To read the FPAA statement visit this link. For further information contact Tracey Hutt, Director Workforce Education and Development via email. 

 

¹ https://www.theguardian.com/world/2019/may/17/we-have-to-fight-alabamas-extreme-abortion-ban-sparks-wave-of-activism

² https://www.researchgate.net/publication/26677181_Unsafe_Abortion_Unnecessary_Maternal_Mortality

80% of new HIV cases transmitted by undiagnosed or untreated people

Healio, March 18, 2019

In 2016, more than 80% of new HIV infections in the United States were transmitted by individuals who either did not know they were infected with HIV or had been diagnosed but were not receiving care, according to data released on the first day of the National HIV Prevention Conference in Atlanta.