Update on multi-drug resistant shigella

SHINE SA, 7/3/2019

The shigella outbreak is continuing in South Australia. This is to advise clinicians to be on alert for a potential increase in shigella cases, and to highlight updated recommendations on treatment as released by the Communicable Disease Control Branch (CDCB).

The outbreak is predominantly in men who have sex with men (MSM) and there is a potential for further increase in numbers related to a larger outbreak in Victoria and NSW. We encourage you to be alert for clients who have recently traveled interstate.The CDCB is now recommending that patients with confirmed multi-drug resistant (MDR) shigella (or at risk of MDR shigella while awaiting sensitivities) be treated with five days of Ceftrixaone 1g IV, rather than 1 day (as recommended in the Public Health Alert issued in December 2018).

Gonorrhoea: Drug Resistance in Australia

Australian Federation of AIDS Organisations (AFAO), 26 June 2018

There has long been concern globally about the potential emergence of drug resistant STIs. In response, the World Health Organisation released new treatment guidelines for three common STIs – chlamydia, gonorrhoea and syphilis – in 2016.

At present, strains resistant to first line treatment of syphilis and chlamydia are not common and not a concern in Australia. There is, however, a growing level of concern about gonorrhoea. This paper therefore focuses on the likelihood and implications of the emergence of drug resistant cases of gonorrhoea in Australia. It also highlights treatment options in Australia and current and emerging strategies for preventing drug resistant gonorrhoea.

Download paper: AFAO Brief – Gonorrhoea – Drug Resistance in Australia – 26 June 2018

‘People are scared’: the fight against a deadly virus no one has heard of

Guardian Australia, Tue 24 Apr 2018 

An Aboriginal woman – we’ll call her B – is sitting in a dry creek bed outside her community and telling the world “this is a very bad disease. But we have to talk in a way not to shame people. Not telling them straight out. Telling them gently and quietly.”

B is talking about a sickness that has killed her family member and is a potential tragedy facing Aboriginal communities in central Australia, who have the world’s highest rates of a fatal, human immune virus for which there is no current cure, no treatment and no coordinated public health response.

Human T-lymphotropic virus type 1 (HTLV-1) is transmitted through sexual contact, blood transfusion and from mother to child by breastfeeding. It can cause a rapidly fatal form of leukaemia. Some people die within weeks of diagnosis. HTLV-1 also causes inflammation of the spinal cord leading to paralysis, severe lung disease known as bronchiectasis and other inflammatory disease.

In five communities around Alice Springs, more than 45% of adults tested have the virus, a rate thousands of times higher than for non-Indigenous Australians.

Two cases of multi-drug resistant gonorrhoea recently detected in Australia: media release

Professor Brendan Murphy, Commonwealth Chief Medical Officer, Australian Government Department of Health 

17 April 2018

Two cases of multi-drug resistant gonorrhoea have been recently detected in Australia. One case was diagnosed in Western Australia and a second case diagnosed in Queensland. 

Multi-drug resistant strains can be difficult to treat and it is important to prevent further spread.

Evidence suggests that one of the Australian cases acquired their infection in Southeast Asia.

The situation is being closely monitored by public health authorities.

Scientists warn that antibiotic-resistant gonorrhoea is on the rise

WHO, 07 July 2017

Every day, more than 1 million sexually transmitted infections are acquired worldwide, and each year an estimated 78 million people are infected with gonorrhoea. New data from 77 countries show that antibiotic resistance is making gonorrhoea much harder – and sometimes impossible – to treat.

The data has been published in PLOS, in two new scientific articles.

Female genital mutilation ban left out of new SA child protection laws

The Advertiser, February 14, 2017 8:02pm

The state’s Guardian for Children has complained that a ban on female genital mutilation has been left out of new South Australian child protection laws.

Read more here