Scientists in Japan have discovered a protein that may have enabled the simian immunodeficiency virus (SIV) to be transmitted to humans. Their findings are published in Cell Host & Microbe. The human immunodeficiency virus (HIV) is believed to have evolved from a SIV that originated in chimpanzees.
A new small-scale human trial of the promising “shock and kill” treatment is starting this week in New York and two sister sites, in Germany and Denmark.
Another small human study will start in January, followed by a larger human shock and kill trial in June.
The HIV research community is increasingly optimistic about this approach to eradicating HIV from infected patients. Such removal of all traces of the virus from an individual’s body would represent an actual cure.
Cities with substantial uncircumcised populations in 1950 tended to have higher HIV-2 prevalence from 1985.
In West African cities, male circumcision rates in 1950 were negatively correlated with HIV-2 prevalence from 1985, according to a study published in the open-access journal PLOS ONE by João Sousa from the University of Leuven, Belgium, and colleagues.
Viruses related to the human immunodeficiency virus (HIV) have infected Old World monkeys as far back as 16 million years ago, according to a new study. The research provides insight into how monkeys evolved and adapted to the simian version of HIV, and why some viruses can jump from one species to another.