HIV-infected vaginal cells do not transmit HIV if plasma viral load is undetectable

nam/aidsmap, 15 February 2016

A group of researchers have cleared up an important question about HIV transmission, in experiments on mice. Although HIV-infected CD4 cells persist in the vagina even on antiretroviral therapy (ART) that fully suppresses free HIV in the blood and body fluids, these cells are not anything like numerous enough to pose any transmission threat.

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Progress on a broadly: neutralising HIV vaccine

ABC: The Health Report, Monday 27 July 2015 5:50PM

For people diagnosed with HIV, an effective vaccine is something of a holy grail. It would allow serodiscordant couples to manage the possibility of transmission, and improve outcomes for millions of HIV-positive cases, many of which are in sub-Saharan Africa.

Vaccines have been tried before: two different HIV vaccines were tested in Thailand, reducing transmission rates by close to 30 per cent.

Now, researchers at the National Institutes of Health in the US are trying to make HIV transmission a thing of the past, by strategically designing broadly neutralising antibodies based on samples taken from patients with chronic HIV.

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