New HIV strain reminds us that innovation is urgent and fundamental

CNN, Updated November 8, 2019

For the first time in 19 years, a team of scientists has detected a new strain of HIV.

The strain is a part of the Group M version of HIV-1, the same family of virus subtypes to blame for the global HIV pandemic. The findings were published Wednesday in the Journal of Acquired Immune Deficiency Syndromes.
HIV has several different subtypes or strains, and like other viruses, it has the ability to change and mutate over time. This is the first new Group M HIV strain identified since guidelines for classifying subtypes were established in 2000. It is important to know what strains of the virus are circulating to ensure that tests used to detect the disease are effective.

 

Update on male contraceptive development

It Takes Two: How Men Fit into Expanding the Family Planning Method Mix

Contraceptive Technology Innovation (CTI) Exchange,  July 5, 2016 9:22 am

The terms “family planning” and “birth control” are synonymous with women’s health and associated with the struggle for equal rights and women’s liberation.  And while the advent of the pill and subsequent advances in contraceptive technology have had enormous implications for women’s health and agency over the last 60 years, male-controlled methods have been responsible for a substantial portion of prevented births for millennia.

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New Male Contraceptives: What’s in the Near-term Pipeline?

Contraceptive Technology Innovation (CTI) Exchange,  July 12, 2016 8:34 pm

Several groups are  researching novel methods of contraception for men from three angles:

  1. Hormonal contraceptives to suppress brain signals that direct the testes to make sperm
  2. Non-hormonal contraceptives that inhibit sperm production in the testes or their maturation prior to ejaculation, and
  3. Novel ways to plug the vas deferens.

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Genetic and Small Molecule Advances Bode Well for Male Contraceptive Development

Contraceptive Technology Innovation (CTI) Exchange, July 20, 2016 11:05 am

On the male side, only three viable methods of contraception have been developed over several millennia (withdrawal, the condom, and vasectomy). New research in hormonal contraception has led to current clinical trials in men; however, as in women, changes in hormone concentrations have adverse effects in men. Thus, to find a non-hormonal contraceptive for men or women would be a game changer.

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Making New Male Contraceptives a Reality

Contraceptive Technology Innovation (CTI) Exchange, July 29, 2016 4:05 pm

A steadfast and devoted group of non-industry scientists, clinicians and advocates—with a desire to bring new and innovative male contraceptive options to market—continues to move the idea forward.  Slow and steady progress is being made, but important challenges still need to be addressed before new male contraceptives become a reality.

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